Back to top
  • (424) 327-4966 (9AM-5PM PST) | FREE Shipping over $100

How to Potentiate Kratom?

Kratom is popular for its many medicinal properties. Some use it to relieve pain. Others use it to ease their anxiety or to increase energy. For users who rely on kratom for its important properties, it can get expensive. Not only that, but you may have to take more to get the same effects.

This is especially true when one develops a large tolerance. Therefore, many people wonder how they can make kratom stronger. First, it is important to know about the issue of tolerance with kratom.

Tolerance to Kratom

If you take kratom often, you build up a tolerance to it. This also happens with other psychoactive substances, like caffeine. The body gets increasingly accustomed to the effects and adjusts.

As tolerance increases, the plant begins to affect you less and less. The longer you take kratom, or the more you take, the more your body will become tolerant to its effects.

One way to reduce your tolerance is to take a break from kratom use. However, you may not have this luxury if you suffer from pain, anxiety attacks, or other health problems that kratom provides a solution to.

There is another way to combat the problem of tolerance to kratom. That solution is potentiation.

What is Potentiation?

Potentiation is the synergistic interaction between two substances. In other words, it is the increased effect of one substance, such as kratom, by taking an unrelated substance.

When you potentiate kratom, you increase the effects without increasing your dose. This is beneficial in a couple ways. For one, taking less powder or capsules is convenient, efficient, and altogether easier.

Another plus is that it is cheaper…and who doesn’t like to save money! Lastly, by taking less kratom you will reduce the amount of tolerance you build to it.

Kratom Potentiators

There are several tried and true ways to make kratom stronger. This list is composed of the best ways to potentiate kratom using spices, other alternative medicines, and even fruit.

It is important to note that kratom affects everyone a little differently. So, you should always be careful when potentiating kratom because the effects will be increased.

1) Caffeine

You likely have at least one source of caffeine at home right now. This could be in the form of coffee, tea, or soda. When combining caffeine with kratom, the effects of both are greater than either one by themselves.

Caffeine can greatly potentiate the stimulating effects of kratom like energy and alertness. If you use kratom for these types of effects, we suggest 50-100mg of caffeine combined with a stimulating strain like White Borneo.

2) Grapefruit Juice

Grapefruit blocks a particular enzyme called CYP3A4. This enzyme helps to metabolize kratom so when grapefruit juice is combined with kratom, it potentiates the effects.

Grapefruit can be eaten with kratom or you can drink a glass of the juice. Some people even like to add it to their kratom tea. Users report that the effects are stronger and last longer when grapefruit is ingested with their usual kratom dose.

3) Valerian Root

Valerian is a flowering plant that is commonly used for its relaxing properties. People use it to relieve anxiety and for sleep. It strongly potentiates the sedation caused by kratom.

If you use kratom for sleep, relaxation, or pain relief this is a good choice. Valerian root increases the positive effects of Red Thai, making this combination a must-try for any kratom user.

4) Chamomile Tea

People commonly drink chamomile tea at night to relax before bed. If you want to increase the relaxing and calming effects of kratom, this is a simple, easy, and cost-effective choice.

The potentiation is less pronounced than with valerian root, but it still is a great choice for those needed to relieve anxiety. If you want to try kratom for your anxiety, we recommend starting with Red Borneo.

5) Magnesium

Magnesium is less of a potentiator and more of a tolerance reducer, but the overall effect is the same. Magnesium can be used to increase all of the effects of kratom from stimulation to pain relief.

6) CBD

Using CBD with kratom can have some beneficial effects. Not only does CBD increase the relaxation caused by kratom, but it also increases the sense of well-being.

Thus, it can help ease anxiety and depression. However, most notably is the positive pain-relieving effects of CBD and kratom. For those with severe pain, we strongly recommend combining CBD with a powerful red strain of kratom like Red Maeng Da.

7) Delta-8-THC

Delta-8-THC can potentiate kratom and relieve anxiety without causing sedation or sleepiness. This combination gives a strong sense of well-being that can eliminate negative thoughts.

Not only that, but it will decrease any anxious thoughts you get from strong stimulating white strains. For a wonderful sense of well-being and anxiety relief, you should try Ketum’s Delta-8-THC with Green Wild kratom.

8) Turmeric

Love curry? Well, turmeric is the main ingredient and is a great potentiator to prolong the effects of kratom. Not only that, but it has numerous health benefits. Kratom may not last as long as you want it to, but to make kratom longer, take a turmeric supplement or include it in your food.


Whether you take kratom to relieve pain, ease your anxiety, or to provide energy, there is a way to potentiate the desired effects. Now, you can limit your tolerance and increase the effects and benefits you want. If you use a different substance to potentiate kratom, we would love to hear about it in the comment section below!

Post a comment

Your email address will not be published. Required fields are marked *